Cells regenerating slowly after 2nd chemo with Leukemia?

My husband (32 yrs old) has AML. He has normal karyotype, has NPM1 and FLT3-TKD mutations. Doctrs decided not to do Bone Marrow transplant unless he relapses in the future. After 1st chemo, cells regenerated very fast and tests were showing slightly NPM1 mutations and no FLT3-TKD ones. Now after the 2nd treatment, doctors said he will get to go home only for like 2 days (unlike last time which was 6 days) to start the next chemo and do next bone marrow test. His chemo ended like 19 days ago and today he had to receive blood transfusions. Is this a bad sign of the illness?